Akkermansia to Support Healthy Weight and Glucose Metabolism

Akkermansia to Support Healthy Weight and Glucose Metabolism

Item #: Akkermansia

Retail price: $69.95

Availability: Usually ships the next business day

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NEW! Pasteurized Akkermansia muciniphila to support healthy weight and glucose metabolism*

Akkermansia muciniphila is a unique bacterium enriched in the mucus layer of the gut.1,2 Higher levels of Akkermansia in the body have been linked to improved metabolism and glucose metabolism, along with improved cardiovascular health, while lower levels have been associated with excess body fat.3*

Akkermansia muciniphila, unlike many of the known probiotic species, is a unique commensal microbe inhabiting the mucus layer, where it can interact closely with host intestinal epithelial cells and immune cells. The gut mucus layer forms a natural defense barrier, and its integrity is vital for maintaining the intestinal health of the host.1 Akkermansia muciniphila is known to utilize mucins (key components of mucus) as nutrient and energy sources and produce beneficial short-chain fatty acids (SCFAs).2 It is believed that through reinforcing gut barrier function, Akkermansia muciniphila supports various bodily functions, such as energy, lipid, and glucose metabolism as well as immune responses.3

Serving size, 1 Tablet. Servings Per Container, 30

Directions: Take 1 tablet per day with a meal or as directed by your healthcare practitioner.

Clinically shown to have a positive impact on weight maintenance*
Includes chromium for healthy glucose metabolism*
Contains EGCG (from green tea extract) to provide additional support for weight maintenance (in concert with a diet and exercise program)*

Clinical Study Data
In a 3-month study, involving 32 overweight/obese, insulin resistant participants, the effects of pasteurized Akkermansia, live Akkermansia, and placebo were examined in a randomized, double-blind, placebo-controlled trial.

The results revealed that pasteurized Akkermansia demonstrated significant improvements in insulin sensitivity, decreased insulin levels, reduced plasma total cholesterol, and decreased body weight, fat mass, and hip circumference when compared to the placebo group.

In contrast, the live version did not exhibit statistically significant changes compared to placebo.

The study results suggest that incorporating pasteurized Akkermansia along with lifestyle modifications for at least 3 months, may offer a multi-faceted approach to improving metabolic health, reducing cardiovascular risk factors, and supporting overall well-being, especially in individuals with overweight/obesity and insulin resistance.

1. Cani PD et al. Nat Rev Gastroentero. 2022:1-13.
2. Macchione LR et al. Eur Rev Med Pharmacol Sci. 2019;23:8075-8083.
3. Santacruz A et al. Brit J Nutr. 2010;104(1):83-92

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
“My functional medicine nutritionist put me on this specific Akkermansia supplement because we discovered I had absolutely no Akkermansia in my gut. I was having a hard time trying to lose any sort of weight and was just constantly gaining uncontrollably. I have been watching my diet and making sure that I move on a daily basis. By adding on this Akkermansia supplement, the weight is literally falling off. I just hope it continues to do so!”

"I usually put on 10+ pounds over the holidays. Without changing my diet at all over the holidays, but taking your supplement, I gained nothing this year."

"I have had a lot of gut issues most of my life and could not lose weight in spite of eating very little. I always said that my metabolism was on the floor. I have taken other probiotics in my life, and I never noticed anything different even though they might have helped in some ways. I have been taking this product for only 8 days now and have lost 3 pounds already with no changes to my diet or sedentary lifestyle. I felt so hopeful that finally I can get down to my normal weight again. I am thrilled with this product and expecting amazing results as it also seems to be helping with my overgrowth of intestinal yeast that I have been miserably battling for about a decade."
Serving Size: 1 Tablet. Servings Per Container: 30

Vitamin D (as cholecalciferol) 5 mcg 25%
Riboflavin (Vitamin B2) 0.21 mg 16%
Chromium (as chromium picolinate) 200 mcg 571%
Green tea leaf (Camellia sinensis) Extract 200 mg **
Epigallocatechin gallate (EGCG) 100 mg **
A proprietary pasteurized Akkermansia muciniphila blend 150 mg (30 billion TFU) **

Other Ingredients: Microcrystalline cellulose, maltodextrin, and magnesium stearate.

Caution: Not for use in children below the age of 18 years. If pregnant, nursing, taking medications, or other nutritional supplements containing green tea extract / EGCG, consult your healthcare practitioner before use. Keep out of the reach of children.

Storage: Store in its original packaging at room temperature, in a dry place away from direct sunlight.